名稱 | Claudin18.2/AGS |
型號 | CBP74131 |
報價 | |
特點(diǎn) | Claudin18.2/AGS |
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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74131Claudin18.2/AGS
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Claudin18.2/AGS Claudin18.2/AGS Claudin18.2/AGS
I. Background | |
Claudin18是位于細(xì)胞膜表面緊密連接的主要成分,它在維持細(xì)胞極性和屏障功能以及促進(jìn)耐酸能力方面起著重要作用。CLDN18的第一個外顯子可以選擇性剪接,形成兩個具有高度同源氨基酸序列的不同剪接突變體(CLDN18.1和CLDN18.2)。跨膜蛋白CLDN18由兩個細(xì)胞外環(huán)、四個跨膜結(jié)構(gòu)域和一個細(xì)胞質(zhì)結(jié)構(gòu)域組成。 | |
II. Introduction | |
Host Cell: | AGS |
Expressed gene: | Claudin18.2 |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | RPMI-1640+10%FBS+2ug/ml puromycin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Binding Assay,FACS |
III. Description of Host Cell Line | |
Species: | Homo sapiens, human |
Tissue: | Stomach |
Disease: | Gastric adenocarcinoma |
Morphology: | Epitheloid |
Growth Properties: | Adherent |
IV. Representative Data | |
1. Claudin18.2/AGS | |
Figure 1. Recombinant Claudin18.2/AGS stably expressing Claudin18.2. |