| 名稱 | hPD-L1/MC38 |
| 型號 | CBPG0001 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | hPD-L1/MC38 |
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電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBPG0001hPD-L1/MC38
- 詳細(xì)內(nèi)容
| CBPG0001 | |
| I. Background | |
| The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and PD-1:PD-L1/2 interaction inhibits T cell activity and allows cancer cells to escape immune surveillance. The PD-1:PD-L1/2 pathway is also involved in regulating autoimmune responses, making these proteins promising therapeutic targets for a number of cancers, as well as multiple sclerosis, arthritis, lupus, and type I diabetes. | |
| II. Introduction | |
| Host Cell: | MC38 |
| Expressed gene: | hPD-L1 |
| Stability: | 32 passages |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | DMEM+10%FBS+5ug/ml blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| III. Description of Host Cell Line | |
| Organism: | Mouse |
| Tissue: | Colon |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| IV. Representative Data | |
Figure 1. Recombinant hPD-L1/MC38 stably expressing hPD-L1. | |
