名稱(chēng) | CCR2/CHO |
型號(hào) | CBP71350 |
報(bào)價(jià) | |
特點(diǎn) | CCR2/CHO 凍存條件:90% FBS+10% DMSO |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > GPCR細(xì)胞株 > CBP71350CCR2/CHO
- 詳細(xì)內(nèi)容
CBP71350 | |
I. Background | |
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1 (CCL2), a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. | |
II. Introduction | |
Host Cell: | CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+5ug/ml puromycin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for CCR2 receptor |
Transducer: | N/A |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 2. CCL 2 effect on CCR2/CHO-K1 clone 11. |