名稱 | PIK3CA p.H1047Y Reference Standard 標準品 |
型號 | CBP10321 |
報價 | |
特點 | PIK3CA p.H1047Y Reference Standard |
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電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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CBP10321 | |
Format | Genomic DNA |
Description | PIK3CA H1047Y is a hotspot mutation that lies within the PI3K/PI4K domain of the Pik3ca protein (UniProt.org). H1047Y confers a gain of function on the Pik3ca protein as indicated by increased phosphorylation of Akt, activation of downstream signaling, and is transforming in cell culture (PMID: 17376864, PMID: 29533785). |
Technical Data | |
DNA Change | c.3139C>T |
AA Change | p.H1047Y |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | NM_006218.1 |
Cosmic ID | COSM774 |
Chr position(GRCh37) | chr3:178952084 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |