| 名稱 | NRAS p.G12S Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10316 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | NRAS p.G12S Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10316NRAS p.G12S Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
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CBP10316 | |
| Format | Genomic DNA |
| Description | NRAS G12S is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12S confers a loss of function on Nras protein as indicated by increased Erk phosphorylation, increased cell preliferation, and is transforming in culture (PMID: 17823240). |
| Technical Data | |
| DNA Change | c.34G>A |
| AA Change | p.G12S |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000369535 |
| Cosmic ID | COSM563 |
| Chr position(GRCh37) | chr1:115258748 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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