名稱 | FBXW7 p.R505C Reference Standard 標準品 |
型號 | CBP10281 |
報價 | |
特點 | FBXW7 p.R505C Reference Standard |
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電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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CBP10281 | |
Format | Genomic DNA |
Description | FBXW7 R505C lies within the WD 4 repeat region of the Fbxw7 protein (UniProt.org). R505C confers a loss of FBXW7-substrate interation and impairs substrate degradation by FBXW7, resulting in sustained NICD and MYC expression (PMID: 17646409). |
Technical Data | |
DNA Change | c.1513C>T |
AA Change | p.R505C |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000281708 |
Cosmic ID | COSM22975 |
Chr position(GRCh37) | chr4:153247289 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |