名稱 | TP53 p.P152L Reference Standard 標準品 |
型號 | CBP10532 |
報價 | |
特點 | TP53 p.P152L Reference Standard |
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聯(lián)系人:蔣經(jīng)理
電話:4008750250
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手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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CBP10532 | |
Format | Genomic DNA |
Description | TP53, tumor protein p53, is a tumor suppressor (PMID: 30562755) and oncogene (PMID: 30577483) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457). |
Technical Data | |
DNA Change | c.455C>T |
AA Change | p.P152L |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100.00% |
Transcript | ENST00000269305.4 |
Cosmic ID | COSM10790 |
Chr position(GRCh37) | chr17:7578475 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |