| 名稱 | AI-Edigene® NRAS p.G13D Reference Standard Pl |
| 型號 | CBP10554 |
| 報(bào)價 |  |
| 特點(diǎn) | AI-Edigene® NRAS p.G13D Reference Standard Plus |
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電話：4008750250
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手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10554AI-Edigene® NRAS p.G13D Reference Standard Pl
- 詳細(xì)內(nèi)容
CBP10554 | |
| Format | Genomic DNA |
| Description | NRAS G13D is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G13D confers a loss of function on Nras protein as indicated by increased GTP-bound Nras, which leads to activation of downstream pathway signaling in cell culture (PMID: 17517660). |
| Technical Data | |
| DNA Change | c.38G>A |
| AA Change | p.G13D |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100.00% |
| Transcript | NM_002524.5 |
| Cosmic ID | COSM573 |
| Chr position(GRCh37) | chr1:115258744 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
